Differential Expression of Peroxisome Proliferator-activated Receptors (PPARs) in the Developing Human Fetal Digestive Tract
نویسندگان
چکیده
منابع مشابه
Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis
BACKGROUND Peroxisome proliferator-activated receptor (PPAR) alpha, betadelta and gamma are nuclear receptors activated by fatty acid metabolites. An anti-inflammatory role for these receptors in airway inflammation has been suggested. METHODS Nasal biopsies were obtained from 10 healthy volunteers and 10 patients with symptomatic allergic rhinitis. Nasal polyps were obtained from 22 patients...
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Nuclear receptors are ligand-activated transcription factors that regulate gene expression in response to small lipophilic compounds such as testosterone [androgen receptor (AR)], oxysterols [liver X receptor (LXR)], estrogen (ER), xenobiotics [pregnane X receptor (PXR)], retinoic acid (RAR), thyroid hormone (TR), bile acids [farnesoid X receptor (FXR)] and vitamin D (VDR). The peroxisome proli...
متن کاملExpression of the Peroxisome Proliferator-Activated Receptors (PPARs) in the Hepatic Stellate Cells
Email: Takeya Sato* [email protected]; Mitsuru Sato [email protected]; Mitsutaka Miura [email protected]; Nobuyo Higashi [email protected]; Da-Ren Wang [email protected]; Shinsuke Suzuki [email protected]; Katsuyuki Imai [email protected]; Naosuke Kojima [email protected]; Haruki Senoo [email protected] * Corresponding author
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Peroxisome proliferator-activated receptors (PPARs) belong to a family of nuclear hormone receptors acting as transcriptional factors, recently involved also in carcinogenesis. Present study was undertaken to evaluate the presence and subcellular localization of different PPAR isoforms (α, β, γ) in healthy endometrial tissue (n = 10) and endometrial carcinoma (FIGO I, endometrioides type, G1, n...
متن کاملPeroxisome Proliferator-activated Receptors
Peroxisome proliferator-activated receptors (PPARs) are members of the ligand-activated nuclear hormone receptor superfamily of transcription factors that includes receptors for steroids, thyroid hormone, retinoic acid, and vitamin D. Upon activation in the cytoplasm, PPARs heterodimerize with retinoid X receptors (RXR) and form a complex that translocates to the nucleus and regulates gene expr...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2000
ISSN: 0022-1554,1551-5044
DOI: 10.1177/002215540004800504